From meditation, wisdom arises;
Without meditation, wisdom wanes.
Knowing this twofold path of gain and loss,
Let one conduct oneself so that wisdom increases.
—The Buddha (Dhammapada 282)
Numerous research studies in the past ten years, especially in the field of neuroscience, have confirmed the positive impact of mindfulness. Many of these research findings are based on advances in brain imaging, such as functional MRI (fMRI), which is used to monitor brain activity during meditation.